Sigmaaldrich offers a number of benzylideneacetone products. Use of the information, documents and data from the echa website is subject to the terms and conditions of this legal notice, and subject to other binding limitations provided for under applicable law, the information, documents and data made available on the echa website may be reproduced, distributed andor used, totally or in part, for noncommercial purposes provided that echa is. It is one of the major constituents of monanthotaxis capea essential oil. The dba is readily s ynthesized b y simple basemediated aldol cond ensation of two equivalents of benzaldehyde with acetone in the. The information given is designed only as a guidance for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered a warranty or quality specification. These benzylidene acetone manufacturing companies are delivering top quality products to the clients on time. Recommendation for benzylidene acetone usage levels up to. It is a paleyellow solid insoluble in water, but soluble in ethanol. Bis2hydroxybenzylideneacetone, a potent inducer of the. Recommendation for z benzylidene acetone usage levels up to. Benzylidene camphor sulfonic acid absorbs uv radiation which is an important cause of premature aging of the skin and in the development of melanoma and other forms of skin cancer. Ac291970000, ac291970010, ac291970050, ac291970100 synonyms. Benzylideneacetone, food and flavor ingredient, flavis no.
Generalizing the reaction conditions, a series of benzylidene acetal containing monosaccharide and disaccharide derivatives, with different functional groups present in them, were treated with the optimized reagent system, and clean removal of benzylidene acetal was observed in all cases. The information provided in this safety data sheet is correct to the best of our knowledge, information and belief at the date of its publication. Dibenzalacetone by aldol condensation 45 aldol synthesis of dibenzalacetone, an organic screen overview. In the united states, sunscreen products are overthecounter otc drugs and only certain ingredients have been. Benzylideneacetone an overview sciencedirect topics. The hazard classification and labelling section shows the hazards of a substance based on the standardised system of statements and pictograms established under the clp classification labelling and packaging regulation. Experimental and computational spectroscopic studies of.
Bis2benzylideneaminophenyl disulfide article pdf available in acta crystallographica section e structure reports online 6712 november 2011 with. In europe, benzylidene camphor sulfonic acid is an approved uv filter, which means that the ingredient can be added to sunscreen products that are designed to protect the skin from the sun. It acts as an inhibitor of the enzyme phospholipase a2 ec 3. Media in category benzylideneacetone the following 6 files are in this category, out of 6 total. Background submission i on the uvfilter 3benzylidenecamphor with the chemical name 3benzylidenebornan2one was submitted by colipa1 in 1996. A regioselective reductive ring opening of benzylidene acetals in carbohydrate derivatives using triethylsilane and molecular iodine is fast and compatible with most of the functional groups encountered in oligosaccharide synthesis, and offers excellent yields. Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, gmp products, impurities and metabolites, apis for veterinary, natural compounds, adcs, stem cell molecule and chiral compounds. Benzylideneacetone article about benzylideneacetone by. Benzylideneacetone is the organic compound described by the formula c 6 h 5 chchc och 3. The substance identifiers displayed in the infocard are the best available substance name, ec number, cas number andor the molecular and structural formulas.
Its original preparation demonstrated the scope of condensation reactions to construct new, complex organic compounds. The reaction conditions are equally effective in thioglycosides. Benzylidene acetone chemical information, properties, structures, articles, patents and more chemical data. Although both cis and transisomers are possible for the. Raluplate benzylidene acetone is used in acid zinc and tin baths as a top brightener. Immediately flush eyes with plenty of water for at lower 15 minutes, occasionally lifting the upper and lower eyes lids. The dba is readily s ynthesized b y simple basemediated aldol cond ensation of two equivalents of benzaldehyde with acetone in. C6h5chchcoch3 a crystalline compound soluble in alcohol, benzene, chloroform, and ether. The clp regulation makes sure that the hazards presented by chemicals are. Information provided on benzylidene acetone 122576 is for reference only and is subject to change. Get medical aid flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. A yellow solid 3, dimethylamino benzylidene acetone was obtained and kept aside overnight. From the laboratories of the rockefeller institute for medical research.
Als environmental does not sell chemicals, but offers analytical lab testing to determine the presence of various elements and chemical compounds. You can also view suppliers in australia, nz or the. It has a role as a flavouring agent, a fragrance, a bacterial metabolite and an ec 3. Suppliers list, emailrfq form, molecular structure, weight, formula, iupac, synonyms for benzylidine acetone cas no. Identification of the substancemixture and of the companyundertaking. Benzylideneacetone is used in the fragrance industry for its sweet pealike odor. Jan 08, 2007 bis 2hydroxybenzylidene acetone is a potent inducer of the phase 2 response through the keap1nrf2are pathway. You will do a double mixedaldol condensation reaction between acetone and benzaldehyde. Structure, properties, spectra, suppliers and links for. The companys origins and strength lie in a profound understanding of the supply and the quality of the diverse raw materials consumed by the flavor and fragrance industries. These are mainly used in electroplating, perfumery and drugs. Bisobenzylidenedglucitol substance information echa. It was previously reported that benzylidene 1ethyl2diazoglu conate, on treatment with acetic acid, with dry hydrogen chloride. Its original preparation demonstrated the scope of condensation reactions to construct new.
Dibenzylideneacetone is used as a component in sunscreens and as a ligand in organometallic chemistry. General description benzylideneacetone is used in the fragrance industry for its sweet pealike odor. Benzylideneacetone article about benzylideneacetone by the. Ac293340000, ac293340100, ac9767, ac9872485, ac9891941, ac9973000 synonyms. Use of the information, documents and data from the echa website is subject to the terms and conditions of this legal notice, and subject to other binding limitations provided for under applicable law, the information, documents and data made available on the echa website may be reproduced, distributed andor used, totally or in part, for noncommercial purposes provided. Berje is a familyowned business that has been in operation for six decades. As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters 150 feet for liquids and at least 25 meters 75 feet for solids. The product is free of halogens and allows the running of the baths at higher temperature. The substance identity section is calculated from substance identification information from all echa databases. There is no warranty of accuracy or completeness of any information contained herein. Benzylideneacetone is the organic compound described by the formula c 6 h 5 chchcoch 3.
It was first prepared in 1881 by the german chemist. This double michael reaction acceptor reacts directly with keap1, the sensor protein for inducers, leading to enhanced transcription of phase 2 genes and protection against oxidant and electrophile toxicities. Search results for benzylideneacetone at sigmaaldrich. Manufacturer of chemical intermediates benzylidene acetone, dibenzalacetone, fenofibric acid and mono ethyl amine offered by rhythm chemicals pvt. Dibenzylideneacetone or dibenzalacetone, often abbreviated dba, is an organic compound with the formula c 17 h 14 o. May 26, 2017 organic chemistry the bivalent aromatic radical c6h5ch. Scientific opinion on flavouring group evaluation 215 fge. Predicted data is generated using the us environmental protection agencys episuite. Seven a,unsaturated cinnamyl ketones from subgroup 3. Dbza is also used extensively in inorganic chemistry as a ligand for palladium 0 as well as platinum 0, both very rare and unreactive metals. Identification of the substancemixture and of the companyundertaking 1. Chemical intermediates benzylidene acetone manufacturer.
Studies suggest that apart from skatole and androstenone, benzylideneacetone may also be one of the volatile compounds, which contributes to the development of boar taint in fat samples. Benzylidene camphor sulfonic acid can be obtained from natural sources, such as the wood of the camphor tree, or it can be produced synthetically. The hazard fields include special hazard alerts air and water reactions, fire hazards, health hazards, a reactivity profile, and details about reactive groups assignments and potentially incompatible absorbents. Synthesis and study of some dibenzylidene acetone derivatives.
Although both cis and trans isomers are possible for the. The scientific committee on cosmetic products and nonfood products intended for. One reagent lane fair lawn, nj 07410 for information in north america, call. Transbenzylideneacetone is the transisomer of benzylideneacetone. On the accuracy of dft methods in reproducing ligand substitution energies for transition metal complexes in solution. Find where to buy products from suppliers in the usa, including. In europe, sunscreen products are considered cosmetic products. One reagent lane fair lawn, nj 07410 for information in north america. Excerpt from erg guide 156 substances toxic andor corrosive combustible watersensitive. In organic chemistry, a benzylidene acetal is the functional group with the structural formula c 6 h 5 chor 2 r alkyl, aryl. Introduction of benzylidene lethyl20 diazogluconate.
Dbza is used as a sun screening agent due to sunlight eventually isomerizing the ketone into cyclobutanes huck and leigh. Once available inventory is depleted, this item will no longer be available. Search for products or services, then visit the american suppliers website for prices, sds or more information. The reaction of an aldehyde with a ketone employing sodium hydroxide as the base is an example of a mixed aldol condensation reaction. Sds certificate of analysis technical inquiry this item cannot be ordered online at this time. Here is the listings of benzylideneacetone cas no 122576, benzylidene acetone manufacturers, suppliers and exporters. Benzylidene acetals are used as protecting groups in glycochemistry. Scientific committee on consumer safety request for a scientific opinion. Bis2hydroxybenzylideneacetone is a potent inducer of the phase 2 response through the keap1nrf2are pathway.